PHS 398 (Rev. 9/04), Biographical Sketch Format Page

A. Positions and Honors.

Positions and Employment

1990 - 1991 Teaching Assistant, Dept. of Psychology, UCLA

1991 - 1993 Teaching Associate, Dept. of Psychology, UCLA

1993 - 1994 Teaching Fellow, Dept. of Psychology, UCLA

1990 - 1994 Graduate Researcher, Dept. of Psychology, UCLA

1994 - 1999 Post Doctoral Fellow, Dept. of Psychiatry and Biobehavioral Sciences, UCLA

1999 - 2006 Assistant Professor, Dept. of Psychiatric and Biobehavioral Sciences, UCLA

2006 - present Associate Professor, Dept. of Psychiatric and Biobehavioral Sciences, UCLA

Honors and Awards

1993 - 1994 Dissertation Research Award, Dept. of Psychology, UCLA

1995 - 1999 Brain Mapping Fellowship, Dept. of Psychiatry, UCLA

2001 ≠ 2004 Cure Autism Now Young Investigator Award

2003 ≠ 2006 National Alliance for Autism Research Award

B. Selected peer-reviewed publications (in chronological order).

1. Au TK, Dapretto M & Song YK 1994 Input versus constraints: Early word acquisition in Korean and English, Journal of Memory and Language, 30:567-582.

2. Bookheimer SY & Dapretto M 1996 Functional Neuroimaging of Language in Children: Current Directions and Future Challenges in Developmental neuroimaging: Mapping the development of brain and behavior, Thatcher RW, Lyon GR, Rumsey J & Krasnegor N (eds.), Academic Press, p.143-155.

3. Dapretto M, Bookheimer SY, Cohen MS & Wang J 1996 Functional MRI of Language in Dyslexic and Normally Developing Children, NeuroImage, 3(3):S434.

4. Dapretto M, Bookheimer SY, Strojwas M & Cohen MS 1998 An fMRI Study of Syntactic Processing Using a Selective Attention Paradigm, NeuroImage, 7:S1.

5. Dapretto M, Bookheimer SY, Strojwas M & Cohen MS 1998 An fMRI Study of Semantic, Phonological, and Orthographic Processing Using a Selective Attention Paradigm, NeuroImage, (7):S171.

6. Dapretto M, Hariri A, Bialik M & Bookheimer SY 1999 Cortical Correlates of Affective vs. Linguistic Prosody: An fMRI Study, NeuroImage, 9(2): S1054.

7. Bookheimer SY, Dapretto M & Karmarkar U 1999 Functional MRI in Children with Epilepsy, Developmental Neuroscience, 21:191-199.

8. Woods RP, Dapretto M, Sicotte NL, Toga AW & Mazziotta JC 1999 Creation and Use of a Talairach-Compatible Atlas for Accurate, Automated Nonlinear Intersubject Registration and Analysis of Functional Imaging Data, Human Brain Mapping, 8:73-79.

9. Dapretto M & Bookheimer SY 1999 Form and Content: Dissociating Syntax and Semantics in Sentence Comprehension, Neuron, 24:427-432.

10. Dapretto M & Bjork EL 2000 The Development of Word Retrieval Abilities in the Second Year and its Relation to Early Vocabulary Growth, Child Development, 71:633-646.

11. Dapretto M & Bookheimer SY 2000 Enhanced Cortical Plasticity Early in Development: Insights from an fMRI Study of Language Processing in Children and Adults, NeuroImage, 11(2):S332.

12. Caplan R, Dapretto M & Mazziotta JC 2000 An fMRI Study of Discourse Coherence, NeuroImage, 11(2):S96.

13. Hernandez A, Dapretto M & Bookheimer S 2000 Language Switching and Language Representation in Spanish-English Bilinguals: An fMRI Study, NeuroImage, 11(2):S340.

14. Caplan R, Dapretto M & Mazziotta JC 2001 An fMRI Study of Discourse Coherence in Childhood Schizophrenia, NeuroImage, 13:S515.

15. Hernandez AE, Dapretto M & Bookheimer SY 2001 Picture Naming in Early vs. Late Bilinguals: An fMRI Study, NeuroImage, 13:S540.

16. Wang A, Dapretto M, Hariri A, Sigman M & Bookheimer SY 2001 Processing Affective and Linguistic prosody in Autism: An fMRI Study, NeuroImage, 13:S621.

17. Hernandez AE, Dapretto M, Mazziotta JC & Bookheimer SY 2001 Language Switching and Language Representation in Spanish-English Bilinguals: An fMRI Study, NeuroImage, 14:510-520.

18. Caplan R & Dapretto M 2001 Making Sense During Conversation: An fMRI Study, NeuroReport, 12:3625-3632.

19. Hernandez A, Valentin V, Dapretto M & Bookheimer S 2002 The Neural Correlates of Grammatical Gender in Spanish: An fMRI Study, Journal of Cognitive Neuroscience, F62 Suppl.

20. Lee SS & Dapretto M 2003 Metaphorical vs. Literal Word Meanings: fMRI Evidence Against a Selective Role of the Right Hemisphere, Journal of Cognitive Neuroscience, A157 Suppl.

21. Caplan R, Dapretto M & Siddarth P 2003 How Schizophrenic Children Make sense of Conversation: An fMRI Study. NeuroImage, 19, E2744-2745.

22. Wang TA, Dapretto M, Lee SS & Caplan R 2003 Making Sense of Conversation: Neural Correlates of Discourse Monitoring in Children with Autism. NeuroImage, 19, E2816-2817.

23. Hernandez AE, Kotz SA, Hofmann J, Valentin VV, Dapretto M & Bookheimer SY 2004 The neural correlates of grammatical gender decisions in Spanish. NeuroReport, 15, 863-866.

24. Dapretto M, Wang AT, Lee SS & Caplan R 2004 Neural Correlates of Syntax, Semantics, and Discourse Monitoring: An fMRI Study in Children with Autism. NeuroImage, 22, E209-211.

25. Wang AT, Dapretto M, Hariri AR, Sigman M & Bookheimer SY 2004 Neural Correlates of Facial Affect Processing in Children and Adolescents with Autism Spectrum Disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 43, 481-490.

26. Dapretto M & Caplan R 2005 An fMRI Study of Discourse Coherence in Typically Developing Children. NeuroReport, 16, 1661-1665.

27. Lee SS & Dapretto M 2006 Metaphorical vs. Literal Word Meanings: fMRI Evidence against a Selective Role of the Right Hemisphere. NeuroImage, 29, 536-544.

28. Dapretto, M, Davies, M, Pfeifer, JH, Sigman, M, Bookheimer, SY, & Iacoboni, M 2006 Understanding Emotions in Others: fMRI Evidence of Mirror Neuron Dysfunction in Children with Autism Spectrum Disorders. Nature Neuroscience, 9, 28-30.

29. Wang, AT, Lee, SS, Sigman, M, & Dapretto, M 2006 Neural Basis of Irony Comprehension in Children with Autism: The Role of Prosody and Context. Brain, 129, 932-943.

30. McNealy, K, Mazziotta, JC, & Dapretto, M 2006 Cracking the Language Code: Neural Mechanisms Underlying Speech Parsing. Journal of Neuroscience (In Press).

31. Wang, AT, Lee, SS, Sigman, M, & Dapretto, M 2006 Developmental changes in the neural basis of interpreting communicative intent. Social Cognitive and Affective Neuroscience (In Press).

C. Research Support.

Ongoing Research Support

Dapretto (PI) 10/01/03-09/30/06

National Alliance for Autism Research

Language and Prosody in Autism: Evidence from fMRI

This research will examine the integrity of the neural systems underlying the processing of the prosodic cues available in speech in high-functioning children with autism.

Role: PI

P01 HD35470 Sigman (PI) 08/31/02-08/30/07

NIH

Determinants of Social Communication Skills in Autism

This project focuses on the neuroanatomical underpinnings of three key processes involved in social cognition, namely, imitation, joint attention, and referencing.

Role: Co-Investigator

RO1 MH067187 Caplan (PI) 09/01/03-07/31/07

NIH

Thought Disorder in Schizophrenic Children: Neuroimaging

This study examines the neural substrate of thought disorder processes in children with early onset schizophrenia.

Role: Co-Investigator

U54 RR021813 Toga (PI) 09/15/04-09/14/09

NIH

Center for Computational Biology (CCB)

This is a proposal to establish a new Center for Computational Biology (CCB). Our goals are to apply computational and mathematical approaches to the study of genes, cells, systems and whole brain.

Role: Project-1 Co-PI

Completed Research Support

1 RO3 DC 05159-01 Dapretto (PI) 08/01/01-07/31/04

NIDCD

Neuroimaging of Language in the Normally Developing Brain

This research investigated the neural network associated with the emergence of high-level linguistic functions in the normally developing brain using both structural and functional neuroimaging.

Role: PI

Dapretto (PI) 08/01/01-07/31/03

M.I.N.D. Research Institute/UC Davis

Language and Communication in the Autistic Brain: Insights from Neuroimaging

This project examined the neural architecture underlying the socio-communicative impairments observed in high-functioning children with autism.

Role: PI

Dapretto (PI) 06/01/01-05/30/03

Cure Autism Now Foundation

Language, Autism, and the Brain: Insights from Neuroimaging

This study combined functional and structural MRI to study the brain systems involved in language processing in high-functioning autistic children.

Role: PI

BIOGRAPHICAL SKETCH Provide the following information for the key personnel and other significant contributors in the order listed on Form Page 2. Follow this format for each person. DO NOT EXCEED FOUR PAGES.

NAME Mirella Dapretto, Ph.D.		POSITION TITLE Associate Professor
eRA COMMONS USER NAME DAPRETTO2
EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such as nursing, and include postdoctoral training.)
INSTITUTION AND LOCATION	DEGREE (if applicable)		YEAR(s)	FIELD OF STUDY
University of California, Los Angeles	B.A.		1988	Psychology
University of California, Los Angeles	M.A.		1990	Developmental Psychology
University of California, Los Angeles	Ph.D.		1994	Developmental Psychology

Principal Investigator/Program Director (Last, First, Middle):	Dapretto, Mirella

BIOGRAPHICAL SKETCH